The Best PDGF-AA Products

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PDGF-AA Recombinant Protein

The best quality, top Anti-Human, Recombinant Protein and else products prices, fast delivery.

Product description

Below is a list of the details of this product.

Product price:

682.50

Product size:

0.002 mg, 0.01 mg

Product catalog no.:

40-457

Product description

Below is a list of the details of this product.

NCBI ID

18590

Uniprot

P20033

Protein's origin

Murine

Recombinant in

E. coli

Rec. PROTEIN GI#

6715566

Vial

Lyophilized

Accession nr

NP_032834.1

Group

recombinants

Source

Mus musculus

Additional source

Recombinants or rec. proteins

Gene name

platelet derived growth factor, alpha

About

This product is for research use only.

Other name of the recombinant

Platelet-derived growth factor subunit A, PDGF-1, PDGF subunit A

Pureity

Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).

SEQUENCE

MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATSNLN PDHREEETGR RRESGKNRKR KRLKPT

Activity

Biological activity was determined by the dose - dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 8 - 10 ng/mL.

Keep at

The lyophilized PDGF-AA recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted PDGF-AA is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing PDGF-AA recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

About recombinant protein

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-AA is a 28.7 kDa disulfide-linked homodimer of two A chains (250 total amino acids).

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