The Best PDGF-AA Products

We invite you to familiarize yourself with our list of PDGF-AA products.

Human CellExp™ PDGF-AA, Human Recombinant

The best quality, top Anti-Human, Recombinant Protein and else products prices, fast delivery.

Product description

Below is a list of the details of this product.

Product price:

344.00

Product size:

10 µg

Product catalog no.:

6476-10

Product description

Below is a list of the details of this product.

Aa sequence

N/A

Recombinant

Yes

Unit

N/A

Binding ability

N/A

Concentration

N/A

Tested activity

N/A

NCBI gene number

5154

NCBI gene

PDGFA

Gene source

Human

Purification

> 95%

NCBI number

P04085

Storage condition

-80°C

Shipping under

gel pack

Physical appearance

Lyophilized

Group

recombinants

Tested applications

SDS-PAGE, N/A

Reesults

200 to 1000 ng/ml

Source

Human 293 cell expressed

Additional source

Recombinants or rec. proteins

Level of endotoxin

<1.0 EU per 1 μg of protein

Before use

Centrifuge the vial prior to opening.

Synonym

Human Cellexp Human Recombinant PDGF-AA

Physical properties

Lyophilized from a solution of 10 mM AcOH.

Molecular weight

35, 40 and 45 kDa, homodimer, glycosylated

Notes

For Research Use Only! Not to be used in humans

How to reconstitute

Reconstitute in sterile PBS containing 10 mM AcOH.

Other name

Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.

Biological activity

ED₅₀ is typically 200 to 1000 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of 3T3 cells.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Background

PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB.

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